Healthy cell lines

bEnd.3 Cell Line: The bEnd.3 cell line is a mouse brain endothelial cell line derived from BALB/c mice. It is commonly used in vascular research and studies of endothelial brain tissue. bEnd.3 cells are particularly valuable for modeling the blood-brain barrier (BBB) and investigating its behavior under conditions like ischemia. By studying bee venom's effects on bEnd.3 cells, we aim to understand how it interacts with brain endothelial cells and its potential impact on the BBB, which is crucial for evaluating the safety of bee venom-based treatments for neurological conditions.

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EaHy926 Cell Line: EaHy926 is a human endothelial hybrid cell line formed by fusing human umbilical vein endothelial cells (HUVECs) with A549 lung carcinoma cells. It is widely used in research to study vascular function, blood-brain barrier integrity, and the effects of therapeutic agents on endothelial cells. Examining the effects of bee venom on EaHy926 cells helps assess its impact on human endothelial cells, providing insights into potential cardiovascular effects and safety.

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293T Cell Line: The 293T cell line is a human embryonic kidney cell line that has been modified to express the SV40 large T antigen, which enhances its ability to replicate. It is extensively used in various fields of research, including gene expression, viral replication, and protein production. Testing bee venom on 293T cells allows us to understand its effects on non-cancerous human cells, helping to establish a safety profile and identify any potential cytotoxicity.